Longevity
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Reversing Biological Age by 10 Years (Clinical)
Clinically available therapies that measurably reverse biological age by 10 years.
Evidence:clinicaltrialsarxivmetaculus Source refresh pending
43.7%progress
Median Predicted Year
2033
P10: 2028 · P90: 2040
Time to Median Prediction
Syncing countdown…
Progress Index Over Time
Proprietary progress score
Prediction Range
P10 / Median / P90 estimates
expertmarketmodel
Why It Moved — Recent Events
30 days laterAug 20
Hourly data refresh:
Automated data refresh
6 days soonerAug 20
Hourly data refresh: 51288 new papers in last 30 days.
Automated data refresh
31 days soonerJul 30
Hourly data refresh: 50659 new papers in last 30 days.
Automated data refresh
Accelerators & Bottlenecks
What speeds it up
Altos Labs primate study shows 20yr reversal
Life Biosciences first human trial 2025
What slows it down
Cancer risk from full reprogramming
Long-term human safety data needed
Forecast methodology: Progress % and predicted years are computed by our proprietary algorithm combining real-money prediction markets (Polymarket, Kalshi), expert forecasts weighted by Brier score accuracy, and hard data trend extrapolation using S-curves fitted to clinical trial progression (ClinicalTrials.gov), AI benchmark scores (HuggingFace), publication velocity (arXiv), and drug approvals (openFDA). P10/P50/P90 represent optimistic, median, and pessimistic scenarios. Updated hourly.